This Kich-Ich & Rally Combo Pack by Ruby Reef eliminates whitespot disease, parasites and pathogenic bacteria, which is safe for any freshwater or saltwater aquarium without harming your fish, corals, invertebrates or plants. These copper free, safe and successful treatments do not tamper with your biological filtration. Kich-Ich and Rally can be used separately or together. The Rally's job is to eliminate marine velvet, clownfish disease, bacterial fin, tail rot, fresh water gill flukes, dinoflagellates, flukes and more, while the Kich-Ich eliminates whitespot disease (ich). Keep these bottles in room temperature for a long shelf life, so your fish can have long-term protection from these issues.